Mold is bad news for the brain.
In a recent journal published in Brain, Behavior and Immunity* we can truly see how mold is bad news for the brain. In this study they dripped Stachybotrys fungi into the nose of rats (can’t imagine having this job!) and found within a short period of time hippocampal immune activation, decreased memory and striking anxiety and as well reduced levels of dopamine .
Study findings included:
1. People are typically exposed to complex mixtures of molds, bacteria, and dust that activate stronger, synergistic immune responses than predicted by adding the effects of the individual stimuli.
2. Mold exposure in homes is underestimated.
3. Most mold exposure is not from spores, but to nanoparticles that are often hundreds, up to as much as a million times, more numerous and penetrate much deeper into the lungs than whole spores and inhaled mold and mycotoxins that essentially “hijack” the olfactory highway into the brain. Of note, it appears the brain is highly vulnerable to mold invasion due to its high fat content and the lipophilic nature of mold. Many mycotoxins can easily cross the blood brain barrier and disrupt not only microglial cells, but also astrocyte that provide the scaffolding and oligodendrocytes, which are important for myelin production.
4. Since exposure to mold often persists for months or even years, it might be expected to cause prolonged innate immune activation of the type already demonstrated to be neurotoxic in a variety of diseases and even if mold exposure is ceased, neuro-immune mechanisms persists for a long time.
5. Mold exposure, both toxic and nontoxic, must be considered another factor like pesticide exposure or smoking that can add to an individual’s burden of inflammation with possible serious consequences for health and behavior.
Bottom line: Mold is a real concern and can negatively impact the wellbeing of our brains! As more studies provide links between neurological conditions and mold exposure, we can only hope that the resulting disorders exhibited by our patients is taken more seriously as a very real medical issue.
Source: Harding, C.F., Pytte, C.L., Page, K.G., Ryberg, K.J., Normand, E., Remigio, G.J., DeStefano, R.A., Morris, D.B., Voronina, J., Lopez, A., Stalbow, L.A., Williams, E.P., Abreu, o., Mold inhalation causes innate immune activation, neural, cognitive and emotional dysfunction, Brain, Behavior, and Immunity (2019), doi: https://doi.org/10.1016/j.bbi.2019.11.006
2/7/2022 03:16:34 am
Mold must be removed as soon as possible. Mold removal professionals should be contacted for assistance in removing mold and for information on how to prevent and control mold growth.
2/13/2022 11:22:42 pm
If you suspect that your depression is caused by poor indoor air quality and mold, seek a professional help!
2/27/2022 12:09:22 am
My friend talked about his plans to move into a new home for his music composer goals. I never knew that prolonged mold exposure could affect your daily life by going straight to your body. Maybe we should start by having his future home inspected for these first before finalizing his move.
11/9/2022 07:05:44 pm
I had no idea that mold exposure comes from nanoparticles. My basement might have mold. I'll have to have an inspection scheduled.
3/1/2023 12:04:43 pm
Thanks so much for explaining that after exposure mold can often persist in the body for months or years. My brother has been noticing that his basement is beginning to smell musty and he's worried about mold forming. We'll have to look into hiring some mold removal specialists to help him test and remove any dangerous mold or damaged material.
3/14/2023 11:16:53 am
I didn't know that mold was similar to pesticide exposure. My wife and I need to get a mold specialist to help with an inspection. I'll have to consider getting a detector.
I never took into account the fact that we might be experiencing prolonged immune activation due to the molds persisting for months or years. I hope that we are not too late when we discovered that we might have them in our basement, because we have lived here for three years now. We should immediately call a mold remediation service tomorrow so that we do not prolong it anymore before we experience any health issues in our family.
5/20/2023 05:28:30 am
Having read the article "Mold Is Bad News for the Brain" on Dr. Suzanne Gazda's website, I wanted to provide some additional insights and information related to the potential effects of mold on the brain.
5/24/2023 05:43:55 am
I recently read your article titled "Mold Is Bad News for the Brain" on suzannegazdamd.com, and I wanted to express my appreciation for shedding light on the potential impact of mold on brain health. Your article provides important insights into the adverse effects that mold exposure can have on neurological well-being.
6/7/2023 12:39:08 am
I came across your article titled "Mold Is Bad News for the Brain" on your website, and I want to express my appreciation for shedding light on the impact of mold on brain health. Mold infestation is a significant concern, and understanding its effects on the brain is crucial for public awareness and well-being.
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by Suzanne Gazda M.D.