I recently was asked to consult on a case of a set designer with multiple years on Broadway who developed Multiple System Atrophy (MSA) in his early 50s. Within five years, he was no longer able to live independently.
MSA is such a horrid disease. Characterized by younger onset, atypical Polycystic Kidney Disease (PKD), bad gait, ataxia, dysarthria, cerebellar strokes and autonomic failure, the slow and awful progression of MSA - like many others - indicates strong genetic linkage disequilibrium.
by Suzanne Gazda M.D.